Molecular genetic studies of schizophrenia
نویسندگان
چکیده
منابع مشابه
Diagnostic Evaluation of Schizophrenia for Genetic Studies
All previously published papers were reproduced with permission from the publishers. To Mattias and Frida The mind is its own place, and in itself Can make a Heav'n of Hell, a Hell of Heav'n-John Milton, Paradise Lost 2 3 ABSTRACT Background: Schizophrenia is one of the top-ten leading disorders causing disability worldwide. Heredity is accepted as a major causative factor but the mechanisms ar...
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The relatively high heritability of schizophrenia suggests that genetic factors play an important role in the etiology of the disorder. On the other hand, a number of environmental factors significantly influence its incidence. As few direct genetic effects have been demonstrated, and there is considerable inter-individual heterogeneity in the response to the known environmental factors, intera...
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Recent advances in genetic epidemiology present excellent opportunities for future high-risk studies of schizophrenia. Improved methods are now available for specifying the natural boundaries of the schizophrenia spectrum and evaluating the mode of inheritance of schizophrenia and its biosocial risk factors. Path-analytic techniques permit the derivation of multifactor indices of both biologica...
متن کاملReport of a workshop on genetic linkage studies in schizophrenia.
A workshop on genetic linkage studies in schizophrenia was held at Columbia University's Arden House Conference Center in October 1989. This report summarizes the contents of invited talks by Drs. Arno Motulsky and T. Conrad Gilliam and the discussions at the five workshop sessions. Topics of the workshop sessions were (1) diagnostic boundaries and hierarchies in schizophrenia, (2) genetic mode...
متن کاملInm-6: Molecular Genetic Basis of Infertility
Background: Sexual reproduction affords the stands for conserving genetic characteristics and sequentially, genetic inconsistency may influence the capability to imitate. Materials and Methods: Research was conducted by subject in PubMed and other databases. Results: A significant number of genotypes have been related with infertility phenotypes and evaluation of precise genes in humans and mod...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2006
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5201571